In the new commercial for Crest Extra White plus Scope Outlast, Ryan's caught off guard by the sudden influx of girls!

Check out Ryan's new Scope commercial! We can tell this was a long grueling shoot for him.

Newly single and ready to conquer the world, sisters Kourtney and Khloé Kardashian leave LA behind and take a chance on a new city with a notoriously hot social scene when they head to sexy South Beach to launch a second DASH boutique. In addition to her duties at the store, Khloé asserts her independence more than ever, embarking on a new career in radio when her late night talk show "Khloé After Dark" takes over the airwaves on Miami's Y100. Produced by Ryan Seacrest Productions and Bunim-Murray Productions, the team behind E!'s hit series "Keeping Up With The Kardashians," "Kourtney and Khloé Take Miami" premieres with a special extended episode on August 16 at 10 pm ET/PT only on E!

See exclusive new footage from E!'s upcoming summer series "Kourtney & Khloe Take Miami." Newly single and ready to conquer the world, sisters Kourtney and Khloé Kardashian leave LA behind and take a chance on a new city with a notoriously hot social scene when they head to sexy South Beach to launch a second DASH boutique. In addition to her duties at the store, Khloé asserts her independence more than ever, embarking on a new career in radio when her late night talk show "Khloé After Dark" takes over the airwaves on Miami's Y100. Produced by Ryan Seacrest Productions and Bunim-Murray Productions, the team behind E!'s hit series "Keeping Up With The Kardashians," "Kourtney and Khloé Take Miami" premieres with a special extended episode on August 16 at 10 pm ET/PT only on E!

This week, Ryan talked to Randy Jackson about how his love for toy trains as a kid led to his support of Amtrak's National Train Day coming up May 9. Also, ryanseacrest.com has your chance for you to win a trip from Washington DC to St. Augustine, FL on Amtrak's Southern Heritage journey down the East coast!

With the holiday season upon us, Ryan felt the least he could do is help kids in need by giving them the opportunity to be Ryan Seacrest for a day.